Item 8.01 Other Events. On August 29, 2025, Iovance Biotherapeutics, Inc. (the “ Company”) updated its corporate presentation that it uses for presentations at healthcare conferences and to analysts, current stockholders, and others. A copy of the Company’s presentation that it intends to use at such events is attached as Exhibit 99.1 and is incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits. (d) Exhibits. Exhibit Description No. ──────────────────────────────────────────────────────────────────────────────────── 99.1 Iovance Biotherapeutics, Inc., Corporate Presentation – August 2025 104 Cover Page Interactive Data File (embedded as Inline XBRL document) SIGNATURES