Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers. For the sole purpose of achieving an equal balance of membership among the three classes of the Board of Directors (the “ Board”) of Solid Biosciences Inc. (the “Company”), effective at 4:00 p. m., Eastern Time, on April 10, 2026, Ilan Ganot, a member of the Board who was serving in Class III (which class will be up for election at the Company’s 2027 Annual Meeting of Stockholders), resigned from the Board. Effective simultaneously with Mr. Ganot’s resignation, the Board decreased the number of Class III directors to three, increased the number of Class I directors to three and appointed Mr. Ganot to fill the vacancy in Class I (with a term expiring at the Company’s 2028 Annual Meeting of Stockholders). Because Mr. Ganot moved from Class III to Class I and therefore will not stand for re-election by our stockholders at the Company’s 2027 Annual Meeting of Stockholders, in keeping with the Company’s commitment to good corporate governance practices, the Company will ask its stockholders to ratify, on an advisory basis, the appointment of Mr. Ganot as a Class I Director at the Company’s 2026 Annual Meeting of Stockholders. There were no changes to any of Mr. Ganot’s compensation arrangements with the Company and there is no compensation due to Mr. Ganot as a result of his resignation from the Board and his appointment to the Board as a Class I Director. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. SOLID BIOSCIENCES INC. Date: April 10, 2026 By: /s/ Alexander Cumbo Name: Alexander Cumbo